Docetaxel works by disrupting the microtubular network in cells, which is essential for cell division and other normal cellular functions. White endeared himself to Jets fans over the last two years with his inspiring play as Zach Wilson's backup. Copyright 2000-2022 Cancer Survivors Network. Last night she was saying that she doesn't know how she is going to get through the next treatment, especially since they supposedly get worse each time. That was on the dose dense A/C. Your doctor may prescribe medication to take before your treatment to help decrease the risk of edema. For cycle 2 I used a great mouthwash - Difflam and have had no sore mouth problems since. Progression-free survival was 2-3 months for both groups. Most people notice that their neuropathy gets better 2 to 4 months after chemotherapy, but it can take up to 1 year to fully go away. If docetaxel does not work or stops working, cabazitaxel (Jevtana) may . Weekly taxol : which days will be worst. And the near close is Sunday because it's Sunday and it has always been pretty precious. I am going to have a chat with them tomorrow ( this is Sunday ) as there must be something they can do. Grapefruit can change how your body absorbs this medication. xx. I have a good support system at home who do just about everything as I have been bed or sofa bound for the last 10 days with just small walks around the house to keep the circulation going. No cancer cells were found, and she was deemed "no evidence of disease". Chemotherapy kills regular cells, as well as cancer cells, and this is why side effects occur . So into hospital she went each time. (Sarcoma, Soft Tissue Sarcoma, Stage 3, Undifferentiated Pleomorphic Sarcoma [UPS]). Avoid things that may worsen the symptoms, such as heavy or greasy/fatty, spicy or acidic foods (lemons, tomatoes, oranges). 4. You should let the oncology care team know if you experience numbness or tingling in the hands and/or feet, as they may need to adjust the doses of your medication. I have to agree, as much as I dont want to get off the couch.. Keeping positive and looking forward to getting to the end of it all. Leg pain also bad tonight, I am on day 5 after first Taxotere chemo so I suppose it's working at its height at the moment, hope it gets better in the coming days! I had infusions every 21 days. For instance, they may continue to work, spend time with family, and exercise. I had constipation, diarrhea so bizarrely both, and then the nausea. Humor can also lessen anxiety and discomfort, allowing cancer patients to talk more openly about their concerns and fears. Except she would always end up in hospital as her temp would spike along with the joint pains. I was neutropenic with infection and just thought it was after effects of chemo. some were bad and some were tolerable plus i also had insomnia because of the steriods.Tell Donna to hang in thereand good luck to you Bob! Grapefruit and grapefruit juice can significantly increase the blood levels of DOCEtaxel. It may get worse after you have your last chemotherapy treatment. I asked my Oncologist if there was any alternative as the side effects are so awful, but there isn't. Taxotere is a part of many peoples cancer journey. xx, No problem you keep strong & you will get through it, I've never cried so much in my life I think it was my way of dealing with it. The steroid is given in pill form or by IV, which will be determined by your healthcare provider. Taxotere Side Effects If you or a loved one want to prepare and learn about the worst days on Taxotere, many patients often receive Taxotere in combination with other chemo drugs. Sorry for the extended message but reading these chats means I'm not alone and I'm not a hypochondriac (as believe me I've thought it) Ask for Zomorph and Oramorph for your bone and joint pain, if it doesn't help ask for Fentynal patches. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. What Are Some Reasons To Buy A Home In Fireside At Desert Ridge? A comprehensive guide to side effects including common and rare side effects when taking Taxotere (Docetaxel for Injection) includes uses, warnings, and drug interactions. Taxotere injections can cause your white blood cell levels to plummet. I have no effects, no CRASH, no anything ((. Took 1 pill starting the day before chemo and for the next 4 days. I shall follow your journey with hope and healing. 5 year old not there yet. That's really great that she had that positive response though, seems worth it and hopeful for the rest of us! Have had one cycle of that and have the second next week. I know how awful Chemo is and I have been lucky that I haven't too many bad side effects I have delt with them as I got them. You could talk to your doctor about your concerns and see if they can give you a lower dose if necessary?They also have pills for most things-I was told that they could probably help with everything but the tiredness. Also, try eating low-fiber, bland foods, such as white rice and boiled or baked chicken. I spent yesterday in A&E with chest pains which turned out to be heartburn and anxiety. It was a big deal but it wasnt. Thank you for the support, hope you are doing well. I have at times reached my lowest and questioned if I can continue to put my body through this poison. Lets hope it does the trick and we can put this behind us. The effects from the chemo were still the typical things though. Keep your fingernails and toenails clean and dry. Get comfortable, own the sofa, the remote, get a body pillow, blanket, soft pyjamas, sweets to suck on, films to watch & any other essential supplies! The Complete Guide That Makes Choosing an HVAC Company Simple, Best Broome Tours: A Guide to This Australian Charm. The mouth issues I suffered with all the way through chemo (didn't have thrush) but would say the mouth part was my worst SE. These Taxotere side effects are less common, meaning they occur in 10-29 percent of patients receiving Taxotere: Vomiting Muscle/bone/joint pain (myalgias and arthralgias) Low platelet count (This can increase your risk of bleeding) Increases in blood tests measuring liver function. The doctor's plan is for me to do the chemo, followed by radiation and then hormone suppressent pills for 5 years. Exposure of an unborn child to this medication could cause birth defects, so you should not become pregnant or father a child while on this medication. Sore throat, swallowing, that was usually first couple of days then I started using Biotene (mouthwash)the day before chemo, the day of chemo, and the day after, and I didnt have any issues with that after at all. Certain cancer treatments can cause sores or soreness in your mouth and/or throat. Its just moving because I felt it moved the chemo through my body faster. I need to eat better to keep up my energy which is at an all time low. It, like other chemotherapy medications, can have severe side effects. My kids are 10 and 5. Hi, not sure if my experiences will help you. This is the start of my second week and although the bone aches have settled, the stomach is at it's worst with terrible cramps and pains. I can't say I am looking forward to next cycle but just want it over. Hopefully this will continue for the last 2 cycles. Thank you for sharing your journey and giving me hope. At least with experiencing this cycle we will be more prepared. I know it is really hard to go back when you know how rough it will make you feel-I tried to look at as a bad dose of flu( a normal person problem)No one would expect you to get out of bed with flu. 10 year old is self sufficient. Signs of a reaction can include: feeling hot or flushed shivering itching a skin rash feeling dizzy a headache feeling breathless or wheezy swelling of your face or mouth pain in your back, tummy or chest. Xx, Hi Berylynn, thank you for the support, we are certainly in this together for you are experiencing some of the same issues as me with this dreadful new chemo. I'm fortunate in that my husband is self employed. The ASCO Genitourinary (GU) Cancers Symposium, which ended on February 18, 2023, was a three-day scientific and educational meeting designed to provide attendees with in-depth, multidisciplinary analysis of the timely topics in the study, diagnosis, and treatment of GU malignancies. You may wear nail polish, but not fake nails. Chemotherapy drugs can deplete your supply of red blood cells, the cells that carry oxygen throughout your body. I was feeling really bad, taking very strong pain killers and they weren't hitting it. Musculoskeletal manifestations usually are transient, occurring within a few days after docetaxel administration lasting about 4 days. - currently getting pumped of the lovely docetaxel! (I too read somewhere that grapefruit can make the side-effects of the drug worse). I'm on my 6th Dox this week, (last one) and I mentioned to my oncologist on 3rd dose that i was awake ALL night on the steroids - I had been prescribed 8mg Dexamethasone twice daily starting day before and finishing on day after Dox. I'm hopeful tomorrow will be a better day. In some cases, you might feel extra hungry or gain weight. I was tired and took naps on my days off. Best wishes Jules xxx. xx, This time 3 years ago, I had just come home from hospital after my mastectomy & full node removal on left side. Write down how you feel each day, it's surprising how this can reduce distress, upset and even ease SE's a little. If you do not have a bowel movement for 2-3 days, you should contact your healthcare team for suggestions to relieve constipation. xxx. If youre suffering from epiphora because of this medication, you might consider a Taxotere lawsuit. Stay strong honey xxxxxxxxxxx, Thank you Lainey66, I will give Kin gingival a try as I feel I am in a vicious circle of mouth problems making eating difficult and tablets which need to be taken with food. As long as I moved and tried to do those things, even though I felt crappy, I would always feel better afterwards. I had no sleepless issues on A/C but on Taxol I did - first meds given me by my Chemo Dr did not help only gave horrible nightmares (which I don't normally have) but my PA switched me to the lowest does of another med and it worked great.It's great to ask for input of experiences BUT There are NONE of us who can tell you what your wife will experience - we are EACH so unique in how our bodies handle the onslaught of the battle - we can tell our stories but we cannot tell you that what happened to/with us will happen for your wife.Susan, I too had AC followed byI too had AC followed by taxol. And it may even boost our immune systems. Men who are treated with this medication should use effective birth control during and for 4 months after the last dose. When meds say 'Take with food' a couple of biscuits or something similar is enough. Taxotere (docetaxel) is a chemotherapy drug used to treat a variety of cancer types including non-small cell lung cancer, prostate cancer, breast cancer, stomach cancer, and head and neck cancer. I have severe bloating which is so uncomfortable its almost painful. Take care, week 3 coming up soon! Plan times to rest during the day and conserve energy for more important activities. As my next cycle came around I was a little apprehensive, however, I can say that the next one was less soul destroying. On Taxol I was comnpletely exhausted on days 2 - 6 and napping/resting did not help at all. Drugmakers developed it from the bark of the Pacific Yew tree, and researchers sometimes refer to it as a plant alkaloid. I was prescribed preventative FEC-T but because I was getting married and honeymooning in July, they decided to do the Taxotere first and cycle 3 was combined with my whole radiotherapy treatment. All the very best for the next treatment, I will think about you when I have mine next Friday. There are a number of things you can do to manage the side effects of docetaxel. Edema happens when fluid collects under your skin and within the tissues outside your circulatory system. Let your oncology care team know if you have any excess bruising or bleeding, including nose bleeds, bleeding gums or blood in your urine or stool. So I feel that is a positive thought. Ask your oncology care team before scheduling dental appointments or procedures. So going through the rest of the horror. Cancer treatment can affect your appetite and, in some cases, the side effects of treatment can make eating difficult. I took Oestrogen suppressing tablets over July and August and restarted chem beginning of September with the FEC. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling . The ninth-largest drop was . An analysis of several studies found that chemotherapy regimens that include an anthracycline are better than a regimen that doesn't include an anthracycline for women diagnosed with early-stage, HER2-negative breast cancer with a high risk of recurrence. Your oncology care team can recommend medications to relieve diarrhea. Taxol/Taxotere and Cytoxan (TC) therapy is one of the most common types of chemotherapy given to women with early-stage breast cancer. Remember your reason for starting chemo. nausea and vomiting. Do not eat grapefruit or drink grapefruit juice during the 2 days before, the day of, and two days after each dose. If you or a loved one want to prepare and learn about the worst days on Taxotere, many patients often receive Taxotere in combination with other chemo drugs. Found the freeze gell hit the joint areas better and gave relief. Was 48mu for EC but took 7Tax was 30mu. Fluid build-up can cause heart failure and poor blood circulation. Then I had actual vomiting, first time ever, because the medications have upset my stomach. Had a DIEP flap reconstruction in August 2016 and am currently waiting to get my date for another op to uplift and reduce my right boob to match the new one. I now feel more prepared for the next 2 cycles but not looking forward to it just getting it over with. Copyright @ 2019 binews.org | All Right Reserved. Worst effect in Cycle 2 and 3 was in lack of taste and the awful chemical tast in my mouth at all times. I ended up in hospital with spiked temperature, although nothing showing in my bloods, but tremendous discomfort and feeling very unwell. If the platelet count becomes too low, you may receive a transfusion of platelets. Shari S. (Breast Cancer, Invasive Ductal Carcinoma (IDC),Triple Positive, Stage 4). xx, I'm with you on this I was the same didn't think I could go on but you do, I'm all done & back to work & back to normal (as normal as can be) good luck keep strong , Thank you for sharing your experience it help me know that it can be done. Found the freeze gell hit the joint areas better and gave relief. Taxotere is a strong chemotherapy drug that doctors prescribe to treat certain types of cancer. Two years after the start of treatment, more than 40% of participants in the trial said they still experienced numbness and tingling in their hands or feet, and 10% rated . I tried everything and to no avail but by the time I had tried everything chemo was over. The recent positive findings seen with docetaxel come from 2 randomized trials: CHAARTED and STAMPEDE. I would get infused on Fridays. The taste improved just before the next treatment. Hopefully the extra meds your gp has prescribed will manage the thrush. I've been prescribed Gabapentin, spoke to my oncologist after the first docetaxel. So would recommend this. With Taxotere, I have had bad stomach aches, back aches, extremely low energy, trouble tasting food, and minimized appetite. When working in your yard, wear protective clothing including long pants and gloves. I had been doing the paracetamol and ibuprofen as previously advised but the Oncology Sister told me that ibuprofen is not suitable for chemo patients as they can interfere with treatment and other medications, since switching I have had more relief and felt better. Yes, this is much tougher than the FEC but it really is worth it x, Thank you biddenden_ sue knowing that others have had the same experience make me accept mine better. If you notice any changes in how you feel during the infusion, let your nurse know immediately. You may also need to take your temperature at home during your treatment to stay on top of fevers. I was diagnosed in August with Breast cancer. You have given me some great pointers and hopefully I can be calmer about my next 2 cycles. Some brief shopping time to restock for the next session. Please consult with your healthcare team regarding the use of these agents and all over the counter medications/supplements while on therapy. (2013) demonstrated that nano-formulation improved plasma PK and tumor delivery of Doc compared to the unprocessed Doc. I do have to rest far more than I used to, although I manage to cope with a busy full time job. Thanks everyone for your messages of support. I am praying for her and hope she will be up and around with new strength soon. My team didn'twarn meof this painful side effect which I think they shouldand now I'm havingthe bone marrow boosting injections too which I know caused me to have severe bone pain with the FEC. APAP vs. CPAP: Whats the Best Machine for Sleep Apnea? I have lost ALL taste buds. Docetaxel belongs to the group of medicines called antineoplastics (cancer medicines). At least week three is getting close, mine starts next Tuesday. Take regular Paracetamol and Ibruprofen all day every day. I can smell but can't taste anything! If the area of injection becomes red, swollen, or painful at any time during or after the injection, notify your care team immediately. You don't sound negative, you just sound disheartened that after following all advice you are still suffering and also that you are finding treatment difficult. What Is the Taxotere Mechanism of Action? Youre coming back off. You should let your doctor or nurse know if you experience any shortness of breath, difficulty breathing, or pain in your chest. neuropathy, or pain caused by nerve damage. In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. The median overall survival (OS) was 81 months . I am just unfortunate to get them all. As the saying goes, "Hindsight is 20/20 . I have other family and friends help but they have their own lives that need to go on. And pineapple sounds a good idea too! I did everything I could. It was stage Three I though thats it,the end. I am still needing sofa days, but hoping to get out soon for a much needed change of scenery and breath of fresh air. In some ways was easier, in others was more taxing (pun intended)! This may vary depending on whether the number of blood cells has returned to normal between each cycle. You should not drive after the infusion until you know how it will affect you. 83 Likes, 0 Comments - Marley Foster (@marley._.foster) on Instagram: "The last few days of school were probably the worst. 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Stage 3, Undifferentiated Pleomorphic Sarcoma [ UPS ] ) the day and energy., the side effects of treatment can affect your appetite and, in others was more (! Of medicines called antineoplastics ( cancer medicines ) change how your body were found, and she was deemed no. Of the Pacific Yew tree, and minimized appetite in your yard, wear protective clothing including long pants gloves! Asked my Oncologist if there was any alternative as the saying goes, & quot ; Hindsight is.! Best Broome Tours: a Guide to this Australian Charm energy, trouble tasting food, and two after... Can do was after effects of docetaxel just want it over with feel more prepared for the last years!
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