But if they become more severe or dont go away, talk with your doctor or pharmacist. Lying down on the bed, and raising your legs. It wasnt reported during studies of the drug. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. If youre concerned about joint pain while using Zetia, talk with your doctor. Zetia is also available in a generic form called ezetimibe. A generic drug is an exact copy of the active drug in a brand-name medication. Absorption isnt affected by food. tender, swollen glands in neck. In clinical studies that lasted an average of 12 weeks, Zetia used with statin drugs was compared with a statin used with a placebo, and a statin used alone. upper respiratory tract infection, including the common cold. This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. If you and your doctor determine that Zetia is safe and effective for you, youll likely take it long term. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. Use these discussion points about familial hypercholesterolemia to prepare for your doctors appointment. However, animal studies dont always predict what will happens in humans. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. And do not stop using Zetia unless your doctor recommends it. Medications in the fibrate drug class may increase the amount of cholesterol thats stored in your gallbladder. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . The insurance company will review the prior authorization request and decide if the drug will be covered. Most of these side effects may go away within a few days or a couple of weeks. I am a stay at home mama to a sweet baby girl, and wife to an amazing h. Zetia is a casebook example of the role the pharmaceutical industry increasingly chooses to play as it intervenes in human lives for corporate profit. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Zetia is sometimes used with medications in the statin drug class. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. Postural orthostatic tachycardia syndrome (POTS) is a condition that causes a number of symptoms when you transition from lying down to standing up, such as a fast heart rate, dizziness and fatigue. They may also check you for signs of muscle breakdown or kidney damage. Zetia shouldnt cause weight gain or weight loss. If left untreated, it can cause your kidneys to stop working properly. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. Lipitor contains the active drug atorvastatin. See the Mild side effects and Serious side effects sections above for more information. Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. Taking Zetia with a statin may cause this side effect. While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. In these studies, 12 weeks of treatment with Zetia and fenofibrate was compared with Zetia taken alone, fenofibrate taken alone, or a placebo (a treatment with no active drug). For more information, see the How Zetia works section below. This list contains examples of serious side effects that can occur with both Zetia and Crestor (when taken individually). You should always consult your doctor or another healthcare professional before taking any medication. Your child can take Zetia with or without food. Your doctor or pharmacist can help you choose one that doesnt have extra ingredients that you dont need. This is not a complete list of side effects and others may occur. Also, if you have a history of heavy drinking or liver damage, be sure to tell your doctor before you begin taking Zetia. The only FDA-approved dosage of Zetia for children is 10 mg once a day. However, its important that you dont stop taking Zetia without first talking with your doctor. This is because fenofibrate is the only fibrate Zetia was studied with, so it isnt known whether Zetia and other fibrate drugs are safe to use together. Zetia may make warfarin (Coumadin, Jantoven) less effective at preventing blood clots. Youll also need to check your insurance plan, as it may only cover one or the other. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . The absence of symptoms doesn't necessarily mean that the cause of POTS is gone as well. The primary symptom of OI is lightheadedness or fainting. Other side effects not listed may also occur in some patients. Tramadol will usually cause a blistering type rash with itching which you do not describe. Fatigue. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. Brand-name medications usually cost more than generics. Zetia comes as a tablet that you swallow. Uses. Medications in this drug class prevent your liver from making new cholesterol. Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. They didnt take Zetia with other drugs that also treat high cholesterol. Qu H, et al. The heart beats faster to pump it up to the brain, but with little success. Zetia is a brand-name prescription drug. People who may be at higher risk of this side effect include those who: Tell your doctor if any of the above apply to you before starting Zetia treatment. The Benary's Giants have large, double blossoms, 4 to 6 inches across, available in a rainbow of . Zetia comes as a tablet that you swallow. About Postural orthostatic tachycardia syndrome. shortness of breath or troubled breathing. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. Cholesterol is made naturally in your liver. Leqvio is a prescription drug used to lower cholesterol. Tried Zetia again to rule out diet causing stomach issues but got same result. What causes POTS? Learn about side effects, costs. Physicians who treat dysautonomia can be located on our Physician List. How long a medication remains good can depend on many factors, including how and where you store the medication. Talk with your doctor or pharmacist if you have trouble swallowing Zetia tablets. Zetia may also be used off-label for other conditions. But new medications can help lower cholesterol and improve heart health. diarrhea*. Here we look at how Zetia and Crestor are alike and different. Ezetimibe may be used alone or with other drugs (such as "statins" or . The generic is considered to be as safe and effective as the original drug. Zetia is sometimes used with medications in the statin drug class. Other interactions can increase side effects or make them more severe. This can increase your risk of side effects from either medication. In order to diagnose POTS, your doctor will need to measure your heart rate when you are sitting at rest. You can take Zetia with or without food. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Statins are commonly prescribed with Zetia to treat certain types of high cholesterol. Dont take an extra dose to make up for your missed dose. Clinical studies looked at Zetia for the treatment of primary hyperlipidemia in adults and in children ages 10 years and older. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. Learn about the drugs dosages, forms, strengths, and more. Talk with your doctor about your health history before you take Zetia. Your body uses cholesterol to make some vitamins, hormones, and fluids that help you digest food. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Do not use more Zetia than your doctor recommends. If youd like to notify the FDA about a side effect youve had with Zetia, visit MedWatch. This can raise your levels of these drugs and increase your risk of side effects. In addition, you may need to watch out for grapefruit. diarrhea. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. It also isnt known what percentage of adults and children experienced diarrhea in clinical studies of other conditions treated with Zetia. It is not yet clear what are the causes of POTS disease. We avoid using tertiary references. When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Zetia should be protected from moisture and shouldnt be stored in areas where it could get damp or wet, such as bathrooms. Medications in this drug class prevent your liver from making new cholesterol. Learn about alternatives like new drugs, A new class of self-injectable medications are showing promise in treating high cholesterol. For primary high cholesterol, Zetia is FDA-approved for use in adults and children* to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet. Do my other medications increase my risk of side effects with Zetia? If you have kidney problems, you may experience even higher levels of Zetia in your body. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. Then theyll monitor whether the drug is working for you and whether you experience any side effects. Zinnia elegans 'Benary's Giant Golden Yellow'. If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. (A class of drugs is a group of medications that work in a similar way.) Total cholesterol is the overall amount of cholesterol found in your blood. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia, or a malfunction of the autonomic nervous system. POTS is a kind of dysautonomia or autonomic nervous disorder. This causes less cholesterol to travel from your small intestine to your liver. Energy Drinks, such as Red Bull, should be avoided in those with POTS. If you drink alcohol, talk with your doctor about whether its safe for you to drink during your Zetia treatment. But over time, heavy alcohol use can damage your liver. It isnt known how often this side effect occurred with Zetia in clinical studies. They can give you tips on how to deal with any side effects that may be bothersome. Medications in this class prevent your small intestine from absorbing cholesterol. POTS-related fatigue is physical in nature . Once diagnosed, many patients face waiting lists as long as two years to get . Learn about the common, mild, and serious side effects it can cause and how to manage them. They can tell you about other medications that may work well for you. Fenofibrate belongs to the fibrate drug class. For information on the effectiveness of Zetia, see the Zetia uses section below. You can use the study as a second opinion to make health care decisions. Some may be a better fit for you than others. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. High cholesterol occurs when you have more cholesterol in your blood than your body needs. Zetia and Crestor have some similar side effects and others that differ. High cholesterol can raise your risk of heart disease. For more information about Zetia, including details about its uses, see this in-depth article on the drug. We've provided a list of the best at-home tests for. Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. 2005-2023 Healthline Media a Red Ventures Company. They may be able to suggest ways to relieve this side effect. Here is a list of conditions that the Food and Drug Administration (FDA) has approved Zetia and Lipitor to treat. And taking it with Zetia and a statin likely wont cause any problems. LDL cholesterol was reduced by 15% more in children who took Zetia and simvastatin than in children who took simvastatin alone. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Cardiology 33 years experience. Zetia isnt known to interact with grapefruit or any other foods. Currently, no medications have been approved by the FDA to treat POTS. Mild side effects of Zetia when taken with a statin (another kind of cholesterol -lowering drug) may include: infection, such as a respiratory . If youre concerned about weight gain while using Zetia, talk with your doctor. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). Zetia is specifically used for high cholesterol caused by: For these uses, your doctor may prescribe Zetia along with other medications to reduce high cholesterol levels. There arent any herbs or supplements that have been specifically reported to interact with Zetia. Started Zetia 10mg and within a few hours horrible stomach pains began as well as constant flatulence. Porphyrias have been associated with POTS symptoms (Stewart & Hensley, 1981). In clinical studies of Zetia used with statin drugs to treat primary hyperlipidemia in adults and in children ages 10 years and older: It isnt known how long adults and children experienced muscle pain while taking Zetia with statin drugs in these clinical studies. They may suggest foods that can help lower your cholesterol and reduce your risk of weight gain. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. dark colored urine. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. To learn about other mild side effects, talk with your doctor or pharmacist, or view Zetias prescribing information. In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. Brand-name medications usually cost more than generics. Ezetimibe may cause side effects. Zetias effect on cardiovascular morbidity and mortality isnt known. Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. It can cause mild side effects and, less commonly, serious side effects. To determine whether you have high cholesterol, your doctor will do a blood test called a lipid panel. Examples of bile acid sequestrants include: Zetia inhibits the intestinal absorption of cholesterol and phytosterols, resulting in a decrease in the transport of intestinal cholesterol to the liver. This is because every persons body responds differently to medications. Zetia generally costs more than Crestor. Your doctor will likely start you on the typical dosage approved to treat your condition. unusual tiredness or weakness. Statin drugs may pass into breast milk. Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. POTS is an unusual condition in which your heart rate speeds up by 30 or more beats per minute with little or no change in blood pressure. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate. When taken together, it should be administered at least 2 hours before or 4 hours after a bile acid sequestrant. Causes of postural tachycardia syndrome (PoTS) It's not clear what causes postural tachycardia syndrome (PoTS). Nausea/Vomiting. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. For example, in studies, some people had to stop taking the drug because their liver enzyme levels increased. A few examples of statins include Lipitor (atorvastatin), Crestor (rosuvastatin), and Zocor (simvastatin). You cannot reliably predict how your body will react to a treatment based on someone elses experience. joint or muscle pain*. In rare cases, taking Zetia with a statin drug may cause rhabdomyolysis (muscle breakdown). Statins shouldnt be used during pregnancy. The causes of POTS are unknown, but the problem is thought to lie in the communication breakdown between the brain and the cardiovascular system. Increased liver enzyme levels are a possible side effect of Zetia. During your Zetia treatment, consider keeping notes on any side effects youre having. However, skip your missed dose if its almost time for your next dose. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. But its not clear whether this side effect occurred in studies of the drug. But in studies, some people had to stop taking the drug due to feeling dizzy. Increased liver enzymes can be a sign of liver damage. But its not clear whether this side effect occurred in studies. The autonomic nervous system controls systems like heart rate, blood pressure, digestion and temperature control, so people with dysautonomia may experience abnormal changes in blood pressure and heart rate, gastrointestinal issues, lightheadedness, fatigue, chest pain . Taking Zetia with cyclosporine (a drug that suppresses your immune system) can raise the levels of both medications in your body. Tell them about all prescription, over-the-counter, and other drugs you take. The following information describes dosages that are commonly used or recommended. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. If you become pregnant while taking Zetia alone or with a statin drug, tell your doctor about your pregnancy right away. Youll likely take Zetia once a day. * Zetia is also approved to treat these conditions in children ages 10 years and older. A Mayo Clinic study published this month in Pacing and Electrophysiology (PACE), suggests that a class of medications more commonly prescribed for older adults is a strong first-line treatment for teenagers with a debilitating condition called postural orthostatic tachycardia syndrome, or POTS. stomach pain. In studies, weight changes didnt occur in people who took the drug. A generic drug is an exact copy of the active drug in a brand-name medication. If you and your doctor decide that Zetia treatment isnt right for you, you simply wont take any more doses. For instance, some interactions can interfere with how well a drug works. Muscle problems are common side effects of statin drugs. 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